Expanding the Medicinal Chemist’s Toolbox to Design BBB-Penetrant Compounds

Time: 11:30 am
day: Day Two

Details:

• The BBB in diseases of the CNS – challenges for the medicinal chemist
• Optimizing compound permeation through the BBB: Overview of the state-ofthe-art
• The impact of hydrogen bond basicity on P-gp mediated efflux

Speakers: